Making precision molecular diagnostics accessible to every laboratory, everywhere.
We democratize access to precision molecular diagnostics through free, open-source computational tools, eliminating expensive hardware barriers that prevent access in resource-limited settings.
Accurate absolute quantification of pathogens is critical for disease surveillance, clinical trials, and treatment monitoring. Current gold-standard technology—Droplet Digital PCR (ddPCR)—costs $60,000-100,000 per instrument, making it inaccessible to 85% of laboratories in disease-endemic countries.
The result: Most labs in resource-limited settings cannot access the precision diagnostics they need most, limiting disease surveillance and research capacity exactly where it matters.
Replace $60,000 hardware with free software
MAK2+ provides ddPCR-equivalent absolute quantification using standard qPCR instruments already available in most laboratories. Using mechanistic kinetic modeling of the PCR amplification process, MAK2+ eliminates the need for expensive specialized equipment while maintaining diagnostic accuracy.
Key Features:
Malaria Parasitemia Quantification
We are validating MAK2+ for Plasmodium quantification in collaboration with malaria research laboratories. Accurate parasite density measurement is critical for:
Timeline: Validation study ongoing • Publication expected Q1 2026 • Multi-country deployment planned for 2026-2027
We believe precision diagnostics should be accessible to every laboratory, regardless of location or resources. By making our tools open source, we ensure:
We're actively seeking:
Malaria research laboratories with ddPCR access for head-to-head comparison studies. Minimal time commitment, co-authorship opportunities, and contribute to global health impact.
Laboratories using qPCR for pathogen quantification. Test MAK2+ on your samples and provide feedback to improve the tool for the global community.
Software developers, computational biologists, documentation writers. Help us build better tools for global health diagnostics.
For collaboration inquiries, partnership opportunities, or questions about our tools, please reach out. We're always happy to connect with researchers, laboratories, and organizations committed to improving global health diagnostics.